Determination of normal values of thymus tissue using neonatal sonography
Neonatal sonografi ile normal timus dokusu değerlerinin belirlenmesi
Mehmet Burak Ozkan 1 * , Sariye Elif Ozyazici Ozkan 2
1 Antalya Research and Training Hospital, Pediatric Radiology Department, Antalya, Turkey
2 Antalya Research and Training Hospital, Neonatology Subunit, Antalya, Turkey
* Corresponding Author
Ortadogu Tıp Derg, Volume 12, Issue 1, pp. 29-33
https://doi.org/10.21601/ortadogutipdergisi.592252
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Abstract
Aim: The aim of this study was to determine the normal volumetric values of thymus tissue by sonography in healthy newborns.
Material and Methods: A total of 220 healthy newborns were evaluated by sonography in the first week of life. The shape, size, diameter and thymic index values and variations of both lobes of thymus were evaluated in terms of gestational age, height and weight values and standards were calculated for the reference population.
Results: According to the shape on transverse scans; the thymus was quadrilateral in 136 neonates (61%), round in 34 (15%), bilobate in 28 (13%), and crescent shaped in 22 (10%) in transverse scan. On longitudinal scans, the thymus was triangular in 154 infants (70%), teardrop shaped in 35 (16%), oval in 31 (14%). The range of the thymic transverse diameter along with confidence interval was 1.1–3.9 (mean 2.36±0.63), that of the sagittal area was 1.3–4.93 cm2 (mean 3.01±0.77), that of the thymic index was 3.1–16.9 cm3 (mean 9.12±2.53), that of the AP (Right) was 0.40–2.40 cm (mean 1.37±0.3), that of the AP (left) was 0.30–3.3 cm (mean 1.69±0.48) and that of the AP (mean) was 0.35–2.83 (mean±1.27).
Conclusion: Knowing the reference values in the neonatal period may be meaningful in evaluating the reactive responses of thymus, which is an immunologic organ in this age population.
Öz
Amaç: Bu çalışmanın amacı sağlıklı yenidoğanlarda, timus dokusunun normal volumetrik değerlerini sonografi ile tespit etmektir.
Gereç ve yöntemler: Yaşamın ilk haftasında toplam 220 sağlıklı yenidoğan ultrasonografi ile değerlendirildi. Her iki timus lobunun şekil, boyut, çap ve timik indeks değerleri ve varyasyonları gebelik yaşı, boy ve kilo değerleri açısından değerlendirilmiş ve referans popülasyon için standartlar hesaplanmıştır.
Bulgular: Enine taramalardaki şekle göre; timus 136 yenidoğanda [%61] dörtgen, 34’ünde [%15] yuvarlak, 28’de [%13] bilobat ve çapraz taramada 22’de [%10] hilal şeklindedir. Boyuna taramalarda timüs 154 bebekte [%70] üçgen şeklinde, gözyaşı şeklinde 35 [%16], ovalinde 31 [%14] idi. Timusal transvers çapın güven aralığı ile birlikte aralığı 1,1–3,9 [ortalama 2,36±0,63], sagital bölgeninki 1,3–4,93 cm2 [ortalama 3,01 ± 0,77], timik indeksin 3,1-16,9 cm3 [Ortalama 9,12±2,53], AP’nin [Sağ] 0,40–2,40 cm [ortalama 1,37±0,3], AP’nin [sol] 0,30-2,3 cm [ortalama 1,69±0,48] ve AP’nin [ortalama] ], 0.35-2.83 idi [ortalama±1,27].
Sonuçlar: Yenidoğan döneminde referans değerlerin bilinmesi, bu yaş popülasyonunda immünolojik bir organ olan timusun reaktif tepkilerini değerlendirmede anlamlı olabilir.
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