Laryngeal neuroendocrine carcinoma

Süleyman Emre Karakurt; Şeyda Akbal; Nurcan Kum; Aykut İkincioğulları; Ayşe Yılmaz Çiftçi; Hacı Hüseyin Dere

doi:10.21601/ortadogutipdergisi.467806

ORTADOĞU TIP DERGİSİ - ORTADOGU MEDICAL JOURNAL

Laryngeal neuroendocrine carcinoma

Laringeal nöroendokrin karsinom

Süleyman Emre Karakurt ¹ ^* , Şeyda Akbal ¹, Nurcan Kum ¹, Aykut İkincioğulları ¹, Ayşe Yılmaz Çiftçi ², Hacı Hüseyin Dere ¹

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Ortadogu Tıp Derg, Volume 11, Issue 3, pp. 353-357

https://doi.org/10.21601/ortadogutipdergisi.467806

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Abstract

Laryngeal neuroendocrine carcinomas are rare tumors of the larynx. A fifty-nine-year-old patient was admitted to our clinic with dysphonia, painful swallowing and weight loss that have been going on for 5 months. Endoscopic examination revealed a mass which extended from left aryepiglottic fold to left ventricle and ventricular fold. Following imaging studies, the patient has undergone direct laryngoscopy and biopsy has been taken. The biopsy was reported as moderately differentiated neuroendocrine carcinoma. After the patient’s refusal of surgical treatment, concomitant radiochemotherapy was performed. Significant regression has been observed in the mass at the seventh month after the treatment. While the first option of treatment is surgical treatment in laryngeal neuroendocrine carcinoma, our case has been observed to respond to concomitant radiochemotherapy.

Keywords: neuroendocrine tumors, carcinoid tumor, laryngeal cancer

Öz

Laringeal nöroendokrin karsinomlar larenksin nadir görülen tümörleridir. Ellidokuz yaşında erkek hasta 5 ay önce başlayan ses kısıklığı, ağrılı yutma ve kilo kaybı şikayeti ile kliniğimize başvurdu. Endoskopik muayenede sol ariepiglottik folddan, sol bant ventrikül ve ventriküle uzanımı olan kitle tespit edildi. Görüntüleme yöntemlerini takiben, hastaya direkt laringoskopi yapıldı ve biyopsi alındı. Biyopsi sonucu orta derecede diferansiye nöroendokrin karsinom olarak raporlandı. Hastanın cerrahi tedaviyi kabul etmemesi üzerine, hastaya eşzamanlı radyokemoterapi planlandı. Tedavi sonrası yedinci ayında hastanın kitlesinde belirgin regresyon gözlendi. Orta derecede diferansiye nöroendokrin karsinomda ilk tedavi seçeneği cerrahi olmak ile birlikte vakamızda, tümörün eş zamanlı radyokemoterapi tedavisine cevap verdiği gözlendi.

Keywords: nöroendokrin tümörler, karsinoid tümör, laringeal kanser

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Citation

Karakurt SE, Akbal Ş, Kum N, İkincioğulları A, Yılmaz Çiftçi A, Dere HH. Laryngeal neuroendocrine carcinoma. Ortadogu Tıp Derg. 2019;11(3):353-7. https://doi.org/10.21601/ortadogutipdergisi.467806

Karakurt, S. E., Akbal, Ş., Kum, N., İkincioğulları, A., Yılmaz Çiftçi, A., & Dere, H. H. (2019). Laryngeal neuroendocrine carcinoma. Ortadoğu Tıp Dergisi, 11(3), 353-357. https://doi.org/10.21601/ortadogutipdergisi.467806

Karakurt, S. E., Akbal, Ş., Kum, N., İkincioğulları, A., Yılmaz Çiftçi, A., and Dere, H. H. (2019). Laryngeal neuroendocrine carcinoma. Ortadoğu Tıp Dergisi, 11(3), pp. 353-357. https://doi.org/10.21601/ortadogutipdergisi.467806

Karakurt SE, Akbal Ş, Kum N, İkincioğulları A, Yılmaz Çiftçi A, Dere HH. Laryngeal neuroendocrine carcinoma. Ortadogu Tıp Derg. 2019;11(3), 353-357. https://doi.org/10.21601/ortadogutipdergisi.467806

Karakurt, Süleyman Emre, Şeyda Akbal, Nurcan Kum, Aykut İkincioğulları, Ayşe Yılmaz Çiftçi, and Hacı Hüseyin Dere. "Laryngeal neuroendocrine carcinoma". Ortadoğu Tıp Dergisi 2019 11 no. 3 (2019): 353-357. https://doi.org/10.21601/ortadogutipdergisi.467806

Karakurt, Süleyman Emre et al. "Laryngeal neuroendocrine carcinoma". Ortadoğu Tıp Dergisi, vol. 11, no. 3, 2019, pp. 353-357. https://doi.org/10.21601/ortadogutipdergisi.467806