Oral cancers and the role of dentists

Hamed Deveci; Dilek Aynur Uğar Çankal

doi:10.21601/ortadogutipdergisi.456800

ORTADOĞU TIP DERGİSİ - ORTADOGU MEDICAL JOURNAL

Oral cancers and the role of dentists

Ağız kanserleri ve diş hekimlerinin rolü

Hamed Deveci ¹ ^* , Dilek Aynur Uğar Çankal ¹

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Ortadogu Tıp Derg, Volume 11, Issue 1, pp. 78-84

https://doi.org/10.21601/ortadogutipdergisi.456800

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Abstract

Cancer is one of the social health problems in Turkey. Oral and pharyngeal cancer, grouped together, is the sixth most common cancer in the world. Most of the oral cancers occur in men aged 50 years and older; however, during last 3 decades, the number of patients worldwide is being diagnosed with head and neck squamous cell carcinoma at a younger age (<45 years old) to be encountered more frequently. Main treatment options for oral and oropharyngeal cancers are surgery, radiotherapy and chemotherapy. Head and neck radiation, chemotherapy, and blood and marrow transplantation can cause oral complications ranging from dry mouth to life-threatening infections. The aim of this review is to update our knowledge on oropharyngeal cancer, to evaluate the effects of cancer therapies on oral region and to emphasize the important role of dentists in diagnosis and treatment planning of cancer.

Keywords: oropharyngeal cancer, incidence, dentists

Öz

Kanser, tüm dünyada olduğu gibi Türkiye’de de en önemli toplumsal sağlık problemlerinden biridir. Ağız ve yutak kanserleri, dünyada en sık izlenen altıncı kanser türüdür. 50 yaş üzeri erkeklerde ağız kanseri görülme riski diğerlerine göre daha fazladır, ancak son 30 yılda dünya çapında baş ve boyun bölgesinde skuamöz hücreli karsinom teşhisi konan genç (45 yaş altında) hasta sayısında artış görülmektedir. Ağız ve yutak kanserlerinin tedavisinde ana seçenekler cerrahi, radyoterapi ve kemoterapidir. Tedavi amacıyla baş boyun bölgesine uygulanan radyoterapi, kemik iliği transplantasyonu ve kemoterapi; ağız kuruluğundan hayatı tehdit eden enfeksiyonlara kadar değişen oral komplikasyonlara yol açabilmektedir. Bu derlemenin amacı ağız ve yutak kanseri ile ilgili bilgilerimizi güncellemek, kanser tedavilerinin ağız bölgesindeki etkisini ve kanser hastalarının tedavisinde diş hekimlerinin rolünün önemini değerlendirmektir.

Keywords: orofarengeal kanser, insidans, diş hekimleri

References

World Health Organization IARC, Cancer Fact Sheets. Available from: http://gco.iarc.fr/today/data/pdf/fact-sheets/cancers/cancer-fact-sheets-29.pdf. /2017
Keskinkılıç B, Gültekin M, Karaca AS et al. Neden ulusal bir kanser programı? In: Türkiye Kanser Kontrol Programı, Keskinkılıç B, Gültekin M, Karaca AS et al (eds) First ed. Ankara: Republic of Turkey, Ministry of Health; 2016: 18-19.
Warnakulasuriya S. Global epidemiology of oral and oropharyngeal cancer. Oral Oncol 2009; 45: 309–16.
American Cancer Society. Cancer. Available from: https://www.cancer.org/cancer/oral-cavity-and-oropharyngeal-cancer/about/what-is-oral-cavity-cancer.html./2017
Harris CM, Ghali GE. Oral Cancer: Etiology, Diagnosis, Classification and Staging. In: Peterson’s Principles of Oral and Maxillofacial Surgery, Milaro MM, Ghali GE, Larsen PE, Waite PD (eds). 3rd ed. Connecticut: People’s Medical Publishing House; 2011; 677-692.
Wood ER. Malignant diseases of the jaws. In: Oral Radiology: Principles and interpretation. White SC, Pharoah MJ (eds). 6th ed. St. Louis: Mosby Elsevier; 2009: 405-6.
Hussein AA, Helder MN, de Visscher JG et al. Global incidence of oral and oropharynx cancer in patients younger than 45 years versus older patients: A systematic review. Eur J Cancer 2017; 82: 115–27.
Tuncer İ. Türkiye’de kanser sıklığı. Türkiye Bilimsel Ve Teknik Araştırma Kurumu, Çukurova Üniversitesi Tıp Fakültesi; 1994.
WHO. Head and nevk cancer. Available from: http://www.who.int/selection_medicines/committees/expert/20/applications/HeadNeck.pdf. 2017
Pullos AN, Castilho RM, Squarize CH. HPV infection of the head and neck region and its stem cells. J Dent Res 2015; 94: 1532–43.
Öztürk B, Coşkun U, Yaman E et al. Oral kavite kanserlerinde risk faktörleri, premalign lezyonlar ve kemoprevensiyon. UHOD 2009; 19: 117–26.
Kumar M, Nanavati R, Modi TG, Dobariya C. Oral cancer: etiology and risk factors: a review. J Cancer Res Ther 2016; 12: 458.
Cuzick J. Preventive therapy for cancer. Lancet Oncol 2017; 18: 472–82.
Herrero R, Quint W, Hildesheim A et al. Reduced prevalence of oral human papillomavirus [HPV] 4 years after bivalent HPV vaccination in a randomized clinical trial in Costa Rica. PLoS One 2013; 8: 68329.
Key TJ, Schatzkin A, Willett WC, Allen NE, Spencer EA, Travis RC. Diet, nutrition and the prevention of cancer. Public Health Nutr 2004; 7: 187–200.
Meurman JH. Infectious and dietary risk factors of oral cancer. Oral Oncol 2010; 46: 411–3.
Kushi LH, Doyle C, McCullough M et al. American Cancer Society guidelines on nutrition and physical activity for cancer prevention. CA Cancer J Clin 2012; 62: 30–67.
Petersen PE. Oral cancer prevention and control–The approach of the World Health Organization. Oral Oncol 2009; 45: 454–60.
Soler M, Bosetti C, Franceschi S et al. Fiber intake and the risk of oral, pharyngeal and esophageal cancer. Int J Cancer 2001; 91: 283-7.
Jafari A, Najafi SH, Moradi F, Kharazifard MJ, Khami MR. Delay in the diagnosis and treatment of oral cancer. J Dent 2013; 14: 146.
Smith RA, Cokkinides V, Eyre HJ. American Cancer Society guidelines for the early detection of cancer, 2003. CA Cancer J Clin 2003; 53: 27–43.
Sankaranarayanan R, Ramadas K, Thomas G et al. Effect of screening on oral cancer mortality in Kerala, India: a cluster-randomised controlled trial. The Lancet 2005; 365: 1927-33.
Esmaelbeigi F, Harirchi I, Omranipour R, vand Rajabpour M. Factors affecting professional delay in diagnosis and treatment of oral cancer in Iran. Arch Iran Med 2014; 17: 253.
Yellowitz J, Horowitz AM, Goodman HS, Canto MT, Farooq NS. Knowledge, opinions and practices of general dentists regarding oral cancer: a pilot survey. JADA 1998; 129: 579-83.
Clovis JB, Horowitz AM, Poel DH. Oral and pharyngeal cancer: knowledge and opinions of dentists in British Columbia and Nova Scotia. J Can Dent Assoc 2002; 68: 415-20.
Hertrampf K, Wenz H-J, Koller M, Wiltfang J. Comparing dentists’ and the public’s awareness about oral cancer in a community-based study in Northern Germany. J Craniomaxillofac Surg 2012; 40: 28-32.
Seoane J, Warnakulasuriya S, Varela‐Centelles P, Esparza G, Dios P. Oral cancer: experiences and diagnostic abilities elicited by dentists in North‐western Spain. Oral Diseases 2006; 12:487-92.
Leao J, Goes P, Sobrinho C, Porter S. Knowledge and clinical expertise regarding oral cancer among Brazilian dentists. Int J Oral Maxillofac Surg 2005; 34: 436-9.
Erbaşar NG, Alpaslan C. Ağız kanserinin önlenmesi ve erken teşhisi konusunda Ankara’daki diş hekimlerinin farkındalığı.Acta Oncologica Turcica 2017; 50: 139-147.
Warnakulasuriya K, Johnson N. Dentists and oral cancer prevention in the UK: opinions, attitudes and practices to screening for mucosal lesions and to counselling patients on tobacco and alcohol use: baseline data from 1991. Oral Diseases 1999; 5: 10-4.
Yellowitz JA, Horowitz AM, Drury TF, Goodman HS. Survey of us dentists'knowledge and opinions about oral pharyngeal cancer. JADA 2000; 131: 653-61.
Marx RE, Cillo JE, Ulloa JJ. Oral bisphosphonate-induced osteonecrosis: risk factors, prediction of risk using serum CTX testing, prevention, and treatment. J Oral Maxillofac Surg 2007; 65: 2397–410.
Nabil S, Samman N. Incidence and prevention of osteoradionecrosis after dental extraction in irradiated patients: a systematic review. Int J Oral Maxillofac Surg 2011; 40: 229–43.
Hupp JR, Ellis E, Tucker MR (editors).Management of the patient undergoing radiotherapy or chemotherapy. In: Contemporary oral and maxillofacial surgery. 5th ed., St. Louis: Mosby Elsevier; 2008: 368 .
Türker M, Yücetaş Ş (editors). Ağız, diş, çene hastalıkları ve cerrahisi. 3. baskı. Ankara: Özyurt Matbaacılık; 2004: 385.
Noury Rad Davaji H. Ankara’da hizmet veren diş hekimlerinin bifosfonat, denosumab ve benzer yan etkilere sahip ilaçları kullanan hastalara yaklaşımı. Uzmanlık tezi, Gazi Üniversitesi Diş Hekimliği Fakültesi, Ağız, Diş ve Çene Cerrahisi Anabilim Dalı, Ankara; 2017.
Tanyeri H, Ofluoğlu D, Karataşlı G, Yılmazer R. Oral kanserlerin erken teşhisinde diş hekimlerinin rolü: iki olgu nedeniyle. J Istanbul Univ Fac Dent 2008; 42: 11.
National Institute of Dental and Craniofacial Research. Available from: https://www.nidcr.nih.gov/oralhealth/topics/cancertreatment. / 2017
Hancock PJ, Epstein JB, Sadler GR. Oral and dental management related to radiation therapy for head and neck cancer. J Can Dent Assoc 2003; 69: 585–90.
Kılınç G, Bulut G, Olgun N, et al. Kanser tedavisi gören çocuklarda tedavinin diş gelişimine olan geç yan etkileri (dört olgu dunumu). Atatürk Üniversitesi Diş Hekim Fakültesi Dergisi 2013; 23: 48-54.
National comprehensive cancer network .Understanding the Oral Complications From Cancer Treatment. Available from: https://www.nccn.org/patients/resources/life_with_cancer/treatment/oral_complications.aspx./ 2017

Citation

Deveci H, Uğar Çankal DA. Oral cancers and the role of dentists. Ortadogu Tıp Derg. 2019;11(1):78-84. https://doi.org/10.21601/ortadogutipdergisi.456800

Deveci, H., & Uğar Çankal, D. A. (2019). Oral cancers and the role of dentists. Ortadoğu Tıp Dergisi, 11(1), 78-84. https://doi.org/10.21601/ortadogutipdergisi.456800

Deveci, H., and Uğar Çankal, D. A. (2019). Oral cancers and the role of dentists. Ortadoğu Tıp Dergisi, 11(1), pp. 78-84. https://doi.org/10.21601/ortadogutipdergisi.456800

Deveci H, Uğar Çankal DA. Oral cancers and the role of dentists. Ortadogu Tıp Derg. 2019;11(1), 78-84. https://doi.org/10.21601/ortadogutipdergisi.456800

Deveci, Hamed, and Dilek Aynur Uğar Çankal. "Oral cancers and the role of dentists". Ortadoğu Tıp Dergisi 2019 11 no. 1 (2019): 78-84. https://doi.org/10.21601/ortadogutipdergisi.456800

Deveci, Hamed et al. "Oral cancers and the role of dentists". Ortadoğu Tıp Dergisi, vol. 11, no. 1, 2019, pp. 78-84. https://doi.org/10.21601/ortadogutipdergisi.456800